{"id":31995,"date":"2025-10-27T21:06:43","date_gmt":"2025-10-27T21:06:43","guid":{"rendered":"https:\/\/gpnewswire.com\/news\/pumping-irony-a-proliferation-of-pills\/"},"modified":"2025-10-27T21:06:43","modified_gmt":"2025-10-27T21:06:43","slug":"pumping-irony-a-proliferation-of-pills","status":"publish","type":"post","link":"https:\/\/gpnewswire.com\/news\/pumping-irony-a-proliferation-of-pills\/","title":{"rendered":"PUMPING IRONY: A Proliferation of Pills"},"content":{"rendered":"<p><a href=\"https:\/\/lowninstitute.org\/projects\/medication-overload-how-the-drive-to-prescribe-is-harming-older-americans\/#:~:text=Scope%20of%20Medication%20Overload&amp;text=More%20than%20four%20in%20ten,take%20ten%20drugs%20or%20more.\" rel=\"nofollow noopener\" target=\"_blank\">By some estimates<\/a>, more than 40 percent of U.S. seniors take five or more prescription drugs each day, a rate that has tripled in the past 20 years. I\u2019m now beginning to understand how that accumulation of various pills, known as <a href=\"https:\/\/www.ncbi.nlm.nih.gov\/books\/NBK532953\/\" rel=\"nofollow noopener\" target=\"_blank\">polypharmacy<\/a>, could happen to someone.<\/p>\n<p>After much discussion during my annual wellness visit last week, my doctor increased the dosage of one of my two blood pressure meds and prescribed a new statin for cholesterol control as well as a topical cream to ward off skin cancer eruptions. She also suggested that I begin taking a magnesium supplement and a regular dose of CoQ10 to try to ward off recurring episodes of peripheral neuropathy.<\/p>\n<p>All this for a guy who three years ago rarely even took an aspirin.<\/p>\n<p>But aging often produces surprising ailments, and various factors can contribute to an overfilled medicine cabinet. As <a href=\"https:\/\/medicaltraveltoday.com\/spotlight-interview-cynthia-chioma-nwaubani-pharmd-bcgp-ceo-and-founder-pharmd-live\/\" rel=\"nofollow noopener\" target=\"_blank\">Cynthia Nwaubani, PharmD<\/a>, explains in a recent <a href=\"https:\/\/www.pharmdlive.com\/blog\/too-much-of-a-good-thing-unpacking-the-rise-of-polypharmacy-in-seniors\/\" rel=\"nofollow noopener\" target=\"_blank\"><em>PharmD Live<\/em> blog post<\/a>, seniors tend to develop multiple chronic conditions that providers, following clinical guidelines, treat with multiple types of medications. Those drugs may be prescribed by more than one practitioner, who may or may not be aware of current prescriptions or their potential interactions. Meanwhile, patients often self-medicate with over-the-counter supplements without consulting their physician.<\/p>\n<p>These factors can combine to increase the risk of harmful drug interactions, leading to conditions ranging from vertigo and frailty to internal bleeding and low blood-sugar levels. And those side effects are often treated with \u2014 you guessed it \u2014 more drugs.<\/p>\n<p>Writing in <a href=\"https:\/\/www.nytimes.com\/2024\/04\/22\/well\/live\/medication-prescription-drug-use.html\" rel=\"nofollow noopener\" target=\"_blank\"><em>The New York Times<\/em><\/a>, Knvul Sheikh describes a \u201cprescription cascade\u201d scenario in which a patient takes an over-the-counter medication that spikes their blood pressure, which their physician treats with a calcium channel blocker, which leads to swollen ankles, which requires a diuretic. \u201cSo you just end up chasing side effects of one medication after the next,\u201d <a href=\"https:\/\/www.nytimes.com\/2024\/04\/22\/well\/live\/medication-prescription-drug-use.html#:~:text=%E2%80%9CSo%20you%20just%20end%20up%20chasing%20side%20effects%20of%20one%20medication%20after%20the%20next%2C%E2%80%9D%20Dr.%20Blachman%20said.\" rel=\"nofollow noopener\" target=\"_blank\">notes<\/a> <a href=\"https:\/\/nyulangone.org\/doctors\/1902033137\/nina-blachman\" rel=\"nofollow noopener\" target=\"_blank\">Nina Blachman, MD<\/a>, a geriatrician at the NYU Grossman School of Medicine.<\/p>\n<p>And, as I\u2019m beginning to learn, that can become an exercise in pharmaceutical juggling. After a hypertensive crisis sent me to the ER in 2023, I left with a prescription for an <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-pressure\/in-depth\/ace-inhibitors\/art-20047480\" rel=\"nofollow noopener\" target=\"_blank\">ACE inhibitor<\/a>. My doctor soon afterward added a <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-pressure\/in-depth\/calcium-channel-blockers\/art-20047605\" rel=\"nofollow noopener\" target=\"_blank\">calcium channel blocker<\/a> and, a few months later, a statin. When I began to experience frequent, intense episodes of neuropathy \u2014 numbness and tingling all down the left side of my body \u2014 I suspected the ACE inhibitor was to blame. So, I convinced my doctor to swap that out in favor of an <a href=\"https:\/\/www.mayoclinic.org\/diseases-conditions\/high-blood-pressure\/in-depth\/angiotensin-ii-receptor-blockers\/art-20045009\" rel=\"nofollow noopener\" target=\"_blank\">angiotensin receptor blocker<\/a>.<\/p>\n<p>But the episodes, though less frequent and intense, continued. So we agreed to drop the particular statin I was using, which I learned had developed a reputation for causing these symptoms. That seemed to help, though it didn\u2019t completely alleviate the neuropathy. And we both agreed that I couldn\u2019t expect to control my troubling cholesterol levels without some pharmaceutical intervention, so she prescribed a different statin and advised me to start with a low dose and build up to the optimal level over a two-month period.<\/p>\n<p>She also suspected that the arthritis in my neck may be contributing to the neuropathic annoyances and suggested a regular dose of <a href=\"https:\/\/ods.od.nih.gov\/factsheets\/Magnesium-HealthProfessional\/\" rel=\"nofollow noopener\" target=\"_blank\">magnesium<\/a> may help quiet what appears to be a disturbance of my nervous system. The <a href=\"https:\/\/www.mayoclinic.org\/drugs-supplements-coenzyme-q10\/art-20362602\" rel=\"nofollow noopener\" target=\"_blank\">CoQ10<\/a>? That might offset the side effects of the statin.<\/p>\n<p>My daily pill-taking regimen now includes two blood pressure drugs, a statin, magnesium, CoQ10, saw palmetto for my prostate, and an AREDS 2 supplement for my vision. Oh, and a spoonful of fish oil.<\/p>\n<p>And that doesn\u2019t include the topical cream that sits in the medicine cabinet awaiting the next appearance of basal cell carcinoma. It appears to be a welcome alternative to the flesh carving I suffered during my first dermatological adventure nearly two years ago. I may even ask my doctor about <a href=\"https:\/\/jamanetwork.com\/journals\/jamadermatology\/article-abstract\/2838591\" rel=\"nofollow noopener\" target=\"_blank\">recent research<\/a> suggesting that a daily regimen of vitamin B3 may keep future lesions at bay. What\u2019s one more pill, right?<\/p>\n<p>It\u2019s a humbling ritual for a septuagenarian who not that long ago prided himself on enjoying a drug-free, healthy lifestyle.<\/p>\n<p>At some point, however, another question arises: How do I wean myself from some of these meds? <a href=\"https:\/\/pharmacy.duke.edu\/personnel\/kuldip-patel-pharmd-fashp\" rel=\"nofollow noopener\" target=\"_blank\">Kuldip Patel, PharmD<\/a>, senior associate chief pharmacy officer at Duke University Hospital, tells the<em> Times<\/em> that he and his team review the prescriptions patients are taking upon each hospital admittance or discharge. That doesn\u2019t always happen at other facilities, he adds, but patients can also ask their doctors to evaluate their meds at least once a year.<\/p>\n<p>And don\u2019t hesitate to ask your provider how long you may need to take a certain drug, says <a href=\"https:\/\/www.bruyere.org\/en\/research-barbara-farrell\" rel=\"nofollow noopener\" target=\"_blank\">Barbara Farrell, PharmD<\/a>, a research scientist at the Bruyere Research Institute in Ottawa. Together, you may be able to develop a plan that allows you to gradually taper off the medication as the symptoms diminish.<\/p>\n<p>\u201cThese are questions people should be asking even in their teens and 20s when they\u2019re being started on some of these medications,\u201d <a href=\"https:\/\/www.nytimes.com\/2024\/04\/22\/well\/live\/medication-prescription-drug-use.html#:~:text=%E2%80%9CThese%20are%20questions%20people%20should%20be%20asking%20even%20in%20their%20teens%20and%2020s%20when%20they%E2%80%99re%20being%20started%20on%20some%20of%20these%20medications%2C%E2%80%9D%20Dr.%20Farrell%20said.%20%E2%80%9CThen%20hopefully%20someday%20we%E2%80%99ll%20be%20able%20to%20prevent%20people%20from%20getting%20to%20the%20point%20where%20they%E2%80%99re%20taking%2025%20medications%20all%20together.%E2%80%9D\" rel=\"nofollow noopener\" target=\"_blank\">Farrell advises<\/a>. \u201cThen hopefully someday we\u2019ll be able to prevent people from getting to the point where they\u2019re taking 25 medications all together.\u201d<\/p>\n<p>I\u2019ll be checking back in with my doctor in a couple of months, when we can evaluate the various effects of my expanded drug regimen. Perhaps at that time, we\u2019ll be able to shift some dosages or eliminate some medications altogether. That is, unless some other ailment arises in the interim.<\/p>\n<p>The post <a href=\"https:\/\/experiencelife.lifetime.life\/article\/pumping-irony-a-proliferation-of-pills\/\" rel=\"nofollow noopener\" target=\"_blank\">PUMPING IRONY: A Proliferation of Pills<\/a> appeared first on <a href=\"https:\/\/experiencelife.lifetime.life\/\" rel=\"nofollow noopener\" target=\"_blank\">Experience Life<\/a>.<\/p>","protected":false},"excerpt":{"rendered":"<p>By some estimates, more than 40 percent of U.S. seniors take five or more prescription drugs each day, a rate that has tripled in the past 20 years. I\u2019m now beginning to understand how that accumulation of various pills, known as polypharmacy, could happen to someone. After much discussion during my annual wellness visit last [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":31996,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[43],"tags":[],"class_list":["post-31995","post","type-post","status-publish","format-standard","has-post-thumbnail","category-life"],"publishpress_future_action":{"enabled":false,"date":"2026-10-25 20:46:13","action":"change-status","newStatus":"draft","terms":[],"taxonomy":"category","extraData":[]},"publishpress_future_workflow_manual_trigger":{"enabledWorkflows":[]},"_links":{"self":[{"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/posts\/31995","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/comments?post=31995"}],"version-history":[{"count":0,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/posts\/31995\/revisions"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/media\/31996"}],"wp:attachment":[{"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/media?parent=31995"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/categories?post=31995"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/gpnewswire.com\/news\/wp-json\/wp\/v2\/tags?post=31995"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}